Two teenage boys have now been charged with murdering Jesse Nwokejiobi.
They will appear in court tomorrow (December 1).
And this afternoon detectives arrested a 44-year-old man and a 36-year-old woman from Harston on suspicion of conspiracy to murder.
Both remain in custody at Parkside Police Station.
On Tuesday night police from the Bedfordshire, Cambridgeshire and Hertfordshire Major Crime Unit returned to South London to bring in the two 16-year-olds, who were originally arrested on Friday evening (25 November), for further questioning.
This afternoon they were both charged with murder.
They are due to appear at Huntingdon Magistrate’s Court tomorrow (1 December).
Jesse, 17, died after being stabbed in Cambridge on Saturday, 19 November.
Anyone with information is urged to pass it to the Major Crime Unit online via the Major Incident Public Portal. Anyone without internet access should call 101 and quote Operation Helix.
Two 14-year-old boys and a 17-year-old boy from Cambridgeshire were arrested in connection with the murder on 19 November.
They remain on bail to return to Thorpe Wood on 20 February.